knee osteoarthritis
Conditions
Interventions
None listed
Sponsors
Yu Sugawara
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Individuals aged 18 or older. 2. Individuals capable of fully understanding this treatment and making decisions based on their own free will. 3. Individuals diagnosed with grade 1 or higher knee osteoarthritis based on the Kellgren-Lawrence (KL) grade. 4. Individuals who have experienced poor treatment outcomes or low satisfaction with existing treatments and wish to undergo this treatment. 5. Individuals who have been provided with the informed consent document regarding this treatment, received sufficient explanation, and can provide voluntary written consent.
Exclusion criteria
Exclusion criteria: 1. Individuals who are diagnosed with rheumatoid arthritis in the affected knee. 2. Individuals who are deemed inappropriate by the attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Safety Assessment. 2. The analgesic effect of the AD-MSC-CM adiministration to patients will be evaluated using Numeric Rating Scale(NRS) & Knee Injury and Osteoarthritis Outcome Score(KOOS). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparison of safety and efficacy evaluations using conditioned medium which are used in this study. 2. Comparison of KOOS scores across groups based on the severity of knee osteoarthritis according to the Kellgren-Lawrence (KL) grade. 3. Analysis of KOOS subscores. | — |
Contacts
Public ContactSugawara Yu
Sugawara Orthopedic Clinic
Outcome results
None listed