Coronary Artery Disease, Abnominal Disease
Conditions
Interventions
Aspirin continuation/interruption in the perioperative period of abdominal surgery
Sponsors
Hiroki Shiomi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients with a history of coronary stenting and scheduled for abdominal surgery - Patients on a single antiplatelet agent
Exclusion criteria
Exclusion criteria: - Patients on dual antiplatelet therapy (DAPT) - Patients on anticoagulation therapy - Patients with a history of stent thrombosis - Patients with CHADS2 score >= 5 - Patients at extremely high risk of bleeding and unable to continue preoperative aspirin - Patients incapable of consent, including those under 20 years of age - Other patients for whom either discontinuation or continuation of antiplatelet agents is inappropriate due to high risk, as determined by the treating physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause death/myocardial infarction | — |
Secondary
| Measure | Time frame |
|---|---|
| - [Safety endpoints] major bleedings (TIMI major/minor bleeding) - Death/myocardial infarction (4thUDMI definition)/stroke - Death/myocardial infarction (4thUDMI definition)/myocardial impairment (MINS) - Death/Myocardial infarction (ARC-2 definition)/Stroke - Death - Cardiovascular death - Myocardial infarction (4thUDMI definition) - Myocardial infarction (SCAI definition) - Myocardial injury (MINS) - Stent thrombosis (ARC definition) - Stroke - Cerebral infarction - Cerebral hemorrhage - Coronary revascularization - Major bleeding - Fatal bleeding - Bleeding during non-cardiac surgery - Blood transfusion - Reoperation | — |
Contacts
Public ContactShiomi Hiroki
Kyoto University Hospital
Outcome results
None listed