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A study of treatment of chronic pain with MSC-CM

The Study of the treatment for Chronic Pain from knee osteoarthritis with Human Mesenchymal Stem Cell Conditioned Medium

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1051240003
Enrollment
Unknown
Registered
2024-04-03
Start date
2024-04-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain from knee osteoarthritis

Interventions

None listed

Sponsors

Atsutomo Morishima
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Individuals who is diagnosed as knee osteoarthritis. 2. Those for whom satisfactory pain relief effects were not observed with standard therapy. 3. Individuals who do not wish to undergo treatment with drugs commonly used in standard therapy for chronic pain due to concerns about side effects, and have been deemed suitable for chronic pain treatment with conditioned medium by a physician. The patient selection criteria are as follows: Patients meeting the following criteria will be considered eligible: 1. Individuals aged 18 and above. 2. Individuals with normal decision-making capacity. 3. Individuals who have been provided with the informed consent document regarding this treatment, received sufficient explanation, and can provide voluntary written consent. 4. Individuals for whom the attending physician has recognized the necessity of treatment.

Exclusion criteria

Exclusion criteria: Individuals meeting any of the following conditions will be excluded from the study: 1. Individuals without pain other than nociplastic pain. 2. Patients with a history or suspicion of dementia 3. Users of narcotics or stimulants. 4. Individuals deemed inappropriate by the attending physician.

Design outcomes

Primary

MeasureTime frame
1. Effect of pain on daily life 2. Pain intensity (Numerical Rating Scale; NRS) 3. Kellgren-Lawrence grade

Secondary

MeasureTime frame
subjective symptoms, etc.

Contacts

Public ContactMorishima Atsutomo

Omotesando Wellness Clinic

atsu5426@yahoo.co.jp+81-3-5962-6485

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026