Coronavirus Disease 2019
Conditions
Interventions
None listed
Sponsors
Kayeka Hiroshi
Hirota Yoshio
Fukushima Wakaba
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who meet all of the following 1), 2), and 3) 1) Persons who meet any of the following (a) to (d) (a) Health care workers at Osaka City (Metropolitan) University Hospital (b) Staff of Osaka City Health Bureau * (c) Faculty / Students of Osaka City (Metropolitan) University School of Medicine / Graduate School of Medicine / Graduate School of Nursing (d) Member of "Osaka Clinical Trial Volunteer Association", Osaka City (Metropolitan) University Hospital # * Including Osaka City Health Center # They will be recruited If the expected number of subjects will not be achieved from (a), (b), and (c) 2) Aged 20-64 years 3) Persons who have voluntarily provided written informed consent for participation
Exclusion criteria
Exclusion criteria: Persons who meet any of the following 1) to 4) 1) Those with contraindications for vaccination 2) Those who have been received with COVID-19 vaccines in the past (including participation in clinical trials or clinical studies) 3) Those who have been diagnosed with COVID-19 in the past 4) Those who are judged to be ineligible for research by the principal investigator or the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunogenicity: antibody response against SARS-CoV2-Spike protein | — |
Secondary
| Measure | Time frame |
|---|---|
| (a) Immunogenicity: response of neutralizing antibody against SARS-CoV2 (b) Prevention of laboratory-confirmed COVID-19 - PCR positive after disease onset - Serological infection including or limited to asymptomatic cases (c) Prevention of COVID-19-like diseases (d) Occurence of adverse reactions after vaccination (e) Occurence of diseases suspected to be caused by vaccination | — |
Contacts
Public ContactWakaba Fukushima
Department of Public Health, Osaka Metropolitan University Graduate School of Medicine
Outcome results
None listed