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Randomized Controlled Trial of Prehabilitation Using Protein Supplementation and Grip Strength Training Before Cardiovascular Surgery

Randmized Controlled Trial of Prehabilitation in Patients Undergoing Cardiovascular Surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1050260089
Enrollment
98
Registered
2026-06-24
Start date
2026-07-14
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina or coronary artery stenosis, Valvular disease,Thoracic aortic aneurysm, Adult congenita - Angina or coronary artery stenosis - Valvular disease - Thoracic aortic aneurysm - Adult congenita

Interventions

Grip strength training and protein load

Sponsors

Miyajima Saki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients scheduled to undergo cardiovascular surgery requiring cardiopulmonary bypass or off-pump coronary artery bypass grafting (OPCAB) at Nara Medical University Hospital or Saiseikai Kumamoto Hospital. 2.Patients with cardiovascular diseases classified as New York Heart Association (NYHA) functional class1or 2. 3.Patients aged 18 years or older, regardless of sex. 4.Patients who can provide written informed consent. 5.Patients who can complete a prehabilitation intervention period of at least 14 days before surgery.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing emergency surgery. 2.Patients with psychiatric disorders who are currently receiving treatment from a psychiatrist. 3. Patients unable to communicate in Japanese in daily conversation. 4.Patients with upper extremity paralysis or other conditions that make grip strength training or grip strength measurement impossible. 5.Patients with a severe allergy to dairy products. 6.Patients with severe obesity (BMI >=35 kg/m2) or poor glycemic control (HbA1c >= 8.0%) for whom nutritional supplementation is considered inappropriate or difficult. 7.Patients with chronic kidney disease (CKD) stage 4 or 5 for whom protein supplementation is considered inappropriate or difficult. 8.Patients with New York Heart Association (NYHA) functional class 3 or 4 heart failure. 9.Patients with a history suggestive of symptomatic cerebral ischemia, such as syncope during exercise. 10.Patients with a history of admission to an intensive care unit (ICU), including at another institution, within the past year. 11.Patients who withdraw their informed consent after enrollment. 12.Patients whose scheduled surgery is postponed by 7 days or more after enrollment, regardless of whether the reason is patient-related or hospital-related. 13.Patients who undergo surgery with an intervention period of less than 14 days due to any reason.

Design outcomes

Primary

MeasureTime frame
WHODAS2.0

Secondary

MeasureTime frame
QoR-15,Postoperative delirium,Postoperative complications,Length of hospital stay

Contacts

Public ContactSaki Miyajima

Nara Medical University

K187665@naramed-u.ac.jp+81-744-29-8902

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026