Study of Electrocardiographic QT Interval Changes in Thoracoscopic Lung Surgery

Perioperative QT Interval Changes in Patients Undergoing Thoracoscopic Lung Surgery: A Prospective Cohort Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1050250154

Enrollment

150

Registered

2025-11-25

Start date

2025-11-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung diseases requiring thoracoscopic surgery

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients scheduled for thoracoscopic lung surgery 2) Patients aged 18 or older at the time of consent

Exclusion criteria

Exclusion criteria: 1) Patients with abnormal QTc interval on preoperative ECG (QTc 450 ms in males / > 460 ms in females) 2) Patiets in whom sinus rhythm is not maintained on preoperative ECG 3) Patients with allergy or contraindication to anesthetics (propofol, desflurane, fentanyl, remifentanil, rocuronium, sugammadex, or ropivacaine) 4) Patients scheduled for continued intubation management postoperatively

Design outcomes

Primary

Measure	Time frame
Difference in QTc interval between preoperative and immediate postoperative periods in thoracoscopic lung resection	—

Secondary

Measure	Time frame
- Association between postoperative QTc interval and blood cytokine levels or local anesthetic concentrations - Association between postoperative QTc interval and autonomic nervous system indices (heart rate variability or pupil diameter) - Perioperative changes in QTc interval (from preoperative to postoperative day 1)	—

Contacts

Public ContactKotaro Hori

Osaka Metropolitan Universtiy Graduate School of Medicine

k.hori@omu.ac.jp+81-666452121

Outcome results