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Additive Diagnostic Utility of 1.9-mm EBUS-Guided Intranodal Forceps Biopsy in Sarcoidosis

A Study on the Additive Diagnostic Utility of 1.9-mm Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy for the Diagnosis of Sarcoidosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1050250153
Enrollment
100
Registered
2025-11-25
Start date
2025-11-11
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary sarcoidosis

Interventions

None listed

Sponsors

Nakai Toshiyuki
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients who demonstrate hilar and/or mediastinal lymphadenopathy on chest CT and are clinically and radiologically suspected of having stage I or II sarcoidosis. 2) Patients in whom EBUS-TBNA and EBUS-IFB are planned for the purpose of obtaining a histological diagnosis for the condition described in (1). 3) Patients aged 20 years or older. 4) Patients who have provided written informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1) Patients in whom a histological diagnosis can be obtained from other organs using minimally invasive methods such as percutaneous biopsy. 2) Patients who are clinically suspected of having malignant disease or tuberculous lymphadenitis, or in whom such conditions are suggested by other examinations. 3) Patients with poorly controlled comorbidities (e.g., unstable angina, recent acute myocardial infarction, severe bronchial asthma, active pulmonary infection, heart failure, bleeding tendency), or those with psychiatric disorders/psychiatric symptoms or dementia that interfere with daily living. 4) Patients deemed inappropriate for inclusion by the attending physician for any other reason.

Design outcomes

Primary

MeasureTime frame
Additional diagnostic yield of EBUS-IFB using standard-sized forceps added to EBUS-TBNA.

Contacts

Public ContactToshiyuki Nakai

Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University

tnakai8716@gmail.com+81-6-6645-3916

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026