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The exploration of biomarkers in patients with Non-Segmental Vitiligo Vulgaris

The exploration of blood and stratum corneum biomarkers in Patients with Non-Segmental Vitiligo Vulgaris

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1050250066
Enrollment
50
Registered
2025-07-11
Start date
2025-07-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo Vulgaris

Interventions

None listed

Sponsors

Yokoi Kazunori
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with mild to moderate non-segmental vitiligo vulgaris Subjects over the age of 2 at the time of informed consent

Exclusion criteria

Exclusion criteria: Subjects with skin diseases (atopic dermatitis, psoriasis, ichthyosis, cutaneous lymphoma, severe acne, and alopecia areata) excluding Vitiligo Vulgaris Subjects with a history of tape-induced contact dermatitis, mechanical urticaria, or similar conditions. Subjects who have applied topical medications (including prescription and over-the-counter drugs) to the stratum corneum sampling site on the day of sample collection. Subjects for whom stratum corneum sampling is deemed difficult due to wounds or other conditions at the sampling site, as determined by the principal investigator or co-investigators. Subjects who have received antibody-based therapies within the past 120 days. Subjects who have received systemic immunosuppressants, immunomodulators, or live vaccines within the past 28 days. Subjects who have participated in another clinical trial, post-marketing clinical study, or clinical research involving investigational products within 120 days prior to sample collection, or who are currently participating in such studies. Subjects who are pregnant or currently breastfeeding and who may be pregnant. Subjects who wish to be pregnant during this study Subjects considered inappropriate for the study by the principal investigator or co-investigators of the clinical research

Design outcomes

Primary

MeasureTime frame
A comparative analysis of the stratum corneum proteome, plasma proteome, and blood transcriptome will be conducted to identify distinct molecular signatures.

Contacts

Public ContactKazunori Yokoi

The University of Osaka Hospital

kyokoi@derma.med.osaka-u.ac.jp+81-6-6879-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026