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Research on the pathogenesis of idiopathic urticaria

Identification of self-reactive IgE and self-antigens in chronic idiopathic urticaria

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1050250027
Enrollment
60
Registered
2025-05-22
Start date
2025-05-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic idiopathic urticaria chronic idiopathic urticaria

Interventions

None listed

Sponsors

Fujimoto Manabu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals who meet the diagnostic criteria for chronic idiopathic urticaria as outlined in the 2018 Urticaria Treatment Guidelines. Specifically, individuals who have experienced itchy red patches that appear and disappear within 24 hours for a period of six weeks or longer. 2. Individuals who are 18 years of age or older at the time of consent. 3. Individuals who have provided written consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding women 2. Individuals with atopic dermatitis 3. Individuals who have used omalizumab, an anti-IgE monoclonal antibody, within the past 3 months 4. Other individuals deemed ineligible by the principal investigator or sub-investigator

Design outcomes

Primary

MeasureTime frame
No evaluation items for basic research. The correlation between the following clinical information and clinical sample analysis results will be examined. 1. Basic information: age, gender, how long you have had the disease, Urticaria Activity Score 2. What you have already had: atopic dermatitis, bronchial asthma, allergic rhinitis, angioedema, autoimmune diseases 3. Medications you are taking: antihistamines, antiallergic drugs, steroids, immunosuppressants, biologics 4, Blood values: white blood cell count, leukocyte formula, immunoglobulin, anti-TPO IgG antibodies, antinuclear antibodies

Contacts

Public ContactYutaka Matsumura

The University of Osaka Hospital

ymatsumu@derma.med.osaka-u.ac.jp+81-668793031

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026