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Tamba Active Mind and Bright Aging Study 3

Evaluation of the effectiveness and participation factors of dementia prevention intervention for older adults with vascular risk factors

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1050240132
Enrollment
1200
Registered
2024-09-20
Start date
2024-09-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of cognitive decline, mild cognitive impairment, and dementia cognitive decline, mild cognitive impairment, dementia, Alzheimers disease

Interventions

Encourage participation in one of the following activities (for up to one year). 1) Exercise class (hybrid type, where participants gather at a meeting place and a trainer provides the program online)

Sponsors

Kowa Hisatomo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Tamba City residents who participated in the specified health checkups in Tamba City in FY2024 and who are between 40 and 75 years old at enrollment. 2) Individuals with any of the following vascular risk factors (hypertension and glucose intolerance) Hypertension: Treated for hypertension, systolic blood pressure over 130 mmHg, or diastolic blood pressure over 85 mmHg Impaired glucose tolerance: Treated for diabetes mellitus or HbA1c over 5.6%. 3) Individuals whose score on the Dementia Assessment Sheet for Community-based Integrated Care System-21 items (DASC-21) is between 22 and 30 points or those suspected of being pre-frailty.

Exclusion criteria

Exclusion criteria: 1) Individuals who need to prohibit or restrict exercise, eating, or drinking water due to severe functional impairment 2) Individuals who have been diagnosed with dementia 3) Individuals with apparent cognitive decline 4) Individuals who are unable to converse in Japanese 5) Individuals who cannot undergo cognitive function tests, etc. 6) Individuals judged inappropriate as research participants by their attending physicians or family physicians

Design outcomes

Primary

MeasureTime frame
Compare the change in the composite score on the Nou-KNOW in the participating groups before and after the intervention

Secondary

MeasureTime frame
Pre- and post-intervention comparisons for the participating groups only 1) Change in scores in each domain in the Nou-KNOW. 2) Change in scores for each item of the comprehensive functional assessment (QoL, frailty, etc.) 3) Change in each item of physical function and the Short Physical Performance Battery (SPPB) score 4) Changes in the level of long-term care insurance certification and the use of long-term care insurance and medical insurance Comparison between participating and non-participating groups 1) Compare the changes in each of the assessment items

Contacts

Public ContactHisatomo Kowa

Kobe University

kowa@med.kobe-u.ac.jp+81-78-796-4514

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026