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Retinal image analysis using adaptive optics devices

Retinal image analysis using ultra-high resolution fundus imaging devices utelizing adaptive optics

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1050230199
Enrollment
220
Registered
2024-03-11
Start date
2024-02-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinochoroidal diseases, retinitis pigmentosa, glaucoma, uveiti .etc

Interventions

None listed

Sponsors

Mandai Michiko
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects (1) patients with retinochoroidal diseases, (2) patients with retinitis pigmentosa, (3) patients with glaucoma, (4) patients with uveitis, (5) patients scheduled for transplantation of iPS cell-derived retinal cells, (6) patients after iPS cell-derived retinal cell transplantation. In addition, (7) healthy volunteers will be used to photograph normal eyes. 2. Selection criteria (1) Persons 20 years of age or older. (2) Persons who have consented to participate in this research.

Exclusion criteria

Exclusion criteria: (1) Persons judged by the principal researcher to be inappropriate as research subjects (2) The following persons fall under the contraindications and prohibitions of using the AO fundus imaging device: Those with a history of photosensitivity; those who have recently received photodynamic therapy (PDT) (Please refer to the package insert of the photosensitive substance administered for the prohibited period);those who are taking medicines that may cause photosensitivity

Design outcomes

Primary

MeasureTime frame
1) Morphological observation and quantitative evaluation of photoreceptor cells (cell density, etc.) using m2OCT 2) Morphological observation and quantitative evaluation of retinal pigment epithelial cells using TFI-rtx1 (cell density, etc.) 3) Comparison of captured images of rtx1 and TFI-rtx1

Contacts

Public ContactMichiko Mandai

Kobe City Hospital Organization Kobe City Eye Hospital

e_lab.mandai@kcho.jp+81-78-381-9876

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026