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Ang-1 study by various age groups

The Exploration of age-specific standard values of digital angiopoietin-1 and age-specific response to arm heating.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1050230011
Enrollment
60
Registered
2023-04-11
Start date
2023-11-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy persons Problem studied: Vasculopathy in Systemic Sclerosis. Angiopoietin

Interventions

Participants warm their upper arms near the elbow wearing the holder with the disposable warmer inserted for 7 days.
heat stress, warming

Sponsors

Shima Yoshihito
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) persons who are 20 years old or elder and younger than 80 years old, 2) persons who understand the instruction and description video of the self blood collection kit (DEMECAL) in Japanese, 3) persons who live in Japan, 4) persons who have given written informed consent of their own free will.

Exclusion criteria

Exclusion criteria: 1) persons who take medications that cause bleeding tendency, 2) persons with diabetes mellitus or who have been diagnosed with diabetes mellitus, 3) persons with collagen disease or a history of collagen disease, 4) Persons who are intolerable to alcohol disinfectants, 5) Persons who are physically, temporarily, or geographically unable to post and return the self-blood collection kit, 6) Persons who are deemed inappropriate by the principal investigator.

Design outcomes

Primary

MeasureTime frame
Distribution of Angiopoietin-1 in fingertip blood samples by age groups

Secondary

MeasureTime frame
Changes in Angiopoietin-1 in fingertip blood samp blood samples before and after warming the upper arm with the disposable warmer.

Contacts

Public ContactAkane Watanabe

Graduate school of medicine, Osaka University

a.watanabe@imed3.med.osaka-u.ac.jp+81-6-6105-5710

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026