non-squamous NSCLC with pathological stage I disease surgically-resected non-squamous NSCLC
Conditions
Interventions
None listed
Sponsors
Suda Kenichi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Non-squamous NSCLC patients who received R0 resection Pure solid tumor at preoperative CT examination Patients who received lobectomy and mediastinal LN dissection Pathologically confirmed stage I NSCLC RNA sample is available (cohort 1) RNA sequence data is available (cohort 2) FFPE sample is available (cohort 3)
Exclusion criteria
Exclusion criteria: Patients who received neoadjuvant therapy Patients who died due to postoperative complication within 90 days after pulmonary resection Patients with lost follow up within 5 years In cohort3, patients who were enrolled in cohort 1 or cohort 2 will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Five-year disease free survivals in cohort 2 (Cohort 2 patients will be divided into high risk group vs. low risk group based on biomarker(s) identified in the analysis of cohort 1. Five-year DFS will be compared between high risk group and low risk group) | — |
Secondary
| Measure | Time frame |
|---|---|
| Five-year overall survivals in cohort 2 Five-year disease free and overall survivals in cohort 3 Five-year disease free and overall survivals in patients with EGFR mutation | — |
Contacts
Public ContactKenichi Suda
Division of Thoracic Surgery, Department of Surgery, Kindai University Faculty of Medicine
Outcome results
None listed