Role of Chymase in Anastomotic Stenosis after gastrectomy and esophagectomy

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1050220037

Enrollment

Registered

2022-06-04

Start date

2022-06-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer, esophageal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.underwent total gastrectomy or proximal gastrectomy for gastric cancer 2.underwent gastric tube reconstruction after esophagectomy for esophageal cancer 3.Written informed consent.

Exclusion criteria

Exclusion criteria: 1.Receiving continuous systemic corticosteroid 2.Peritoneal Dissemination, positive lavage cytology 3.Positive margins

Design outcomes

Primary

Measure	Time frame
1.chymase activity 2.Real time polymerase chain reaction of chymase 3.histological analysis	—

Secondary

Measure	Time frame
1.TGF-beta activity 2.Real time polymerase chain reaction of TGF-beta	—

Contacts

Public ContactYoshiro Imai

Osaka Medical and Pharmaceutical University

yoshiro.imai@ompu.ac.jp+81-72-683-1221

Outcome results