Association between synovial bioactive molecule profile and perioperative pain in patients receiving knee arthroplasty.

Association between synovial bioactive molecule profile and perioperative pain in patients receiving knee arthroplasty. - Synovial fluid and perioperative knee pain

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1050210208

Enrollment

100

Registered

2022-03-26

Start date

2022-03-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee arthritis Knee arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are equal or older than 20 years old. Patients with knee osteoarthritis and receive knee arthroplasty who visited the institution during the period of the date of IRB approval and March 31, 2024. Patients who are able to obtain written informed consent about this study. Patients who will receive the same side re-surgery and contralateral postsurgery are considered eligible.

Exclusion criteria

Exclusion criteria: Patients who are unable to answer the questionnaire. Patients whom doctors in charge consider inadequate to participate. Patients with abnormal surgical site condition or pain due to infection etc.

Design outcomes

Primary

Measure	Time frame
The amount of bioactive molecule in knee synovial fluid obtained during the surgery.	—

Secondary

Measure	Time frame
The amount of blood bioactive molecule obtained during the surgery. Association between perioperative pain intensity and questionary result. Association between synovial bioactive molecule amount and perioperative pain intensity.	—

Contacts

Public ContactFumimasa Amaya

Kyoto Prefectural University of Medicine

kpum.palliative.care.med@gmail.com+81-75-251-8177

Outcome results