Type2 diabetes Type2 diabetes
Conditions
Interventions
Participating patients perform the exercise therapy program (aerobic and resistance exercise), as follows. Aerobic exercise: 3-5 days or more per week (without 2 days interval), totaly more than 10 kc
Sponsors
Nishizawa Hitoshi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Type 2 diabetic patients admitted to the Department of Diabetes, Endocrinology, and Metabolism, Osaka University Hospital (regardless of gender), who meet the following criteria 1) Patients aged 20 to 74 years 2) Patients diagnosed with type 2 diabetes by the doctors 3) Patients who have agreed to participate in the program
Exclusion criteria
Exclusion criteria: 1) Patients with type 1 diabetes or secondary diabetes 2) Fasting plasma glucose; 250mg/dl or more 3) Resting blood pressure; 180/110mmHg or more 4) Diabetic nephropathy with stage 3 or more (urinary albumin/creatinine ratio; 300 mg/g Cr or more or persistent proteinuria) 5) Severe neuropathy (sensory and autonomic neuropathy) 6) Unstable diabetic retinopathy such as preproliferative or proliferative retinopathy 7) Unstable macroangiopathy such as cardiovascular disease and peripheral arterial disease 8) Severe liver damage (decompensated cirrhosis, etc.) 9) Heart failure (NYHA; II or more or patients on limited physical activity) 10) Patients at high risk of hypoglycemia 11) Patients whose condition is thought to worsen by whole body vibration (e.g. dizziness, etc.) 12) Patients who are at risk of falling and are judged to have difficulty in performing whole body vibration 13) Female patients who are pregnant or potentially pregnant and are lactating 14) Patients who are judged by the doctors to be inappropriate for participation in the program due to complications (e.g. blindness, decreased ADL, scheduled surgery, uncontrollable active infections, etc.) 15) Patients who are difficult for the doctors to assess the effectiveness of the program (e.g. complications of psychiatric disorders or mental disorders, having difficulty in communicating with medical staff, alcohol-dependent / drug-dependent, planning a long trip during the program, opposed by their families, and a rapid weight loss more than 4.5 kg within 3 months, etc.) 16) Patients that the primary investigator or the doctors consider to be inappropriate for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma hypoxanthine (HX), xanthine (Xan), uric acid (UA), and xanthine oxidoreductase (XOR) activity before and after WBV exercise Body composition evaluated by In Body, grip strength,lower limb extension, and thigh circumference | — |
Secondary
| Measure | Time frame |
|---|---|
| International Physical Activity Questionnaires(IPAQ) Eating behavior questionnaire Food preference questionnaire Exercise function test such as chair-stand test and 6-minute walking distance | — |
Contacts
Public ContactYusuke Kawachi
Department of Metabolic Medicine, Graduate School of Medicine, Osaka University
Outcome results
None listed