Analyzing the impact of aging on the immune system in the context of covid-19 vaccination

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1050210014

Enrollment

200

Registered

2021-05-06

Start date

2021-05-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Subjects working at Kyoto University and aged 20 years old or older at informed consent with no major medical history and other medical problems 2) Subjects aged 65 years old or older at informed consent with no major medical history 3) Subjects who have obtained written consent voluntarily to participate in this trial 4) Subjects who are scheduled to receive COVID-19 vaccination

Exclusion criteria

Exclusion criteria: 1) Subjects who have been administered with drugs that affect the immune system (excluding external preparations) such as immunomodulators (DMARDs, etc.), immunosuppressants, biologics, etc. 2) Subjects who are tested positive for human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), or HTLV-1. 3) Subjects who are otherwise ineligible for this study in the principal investigator's or subinvestigator's opinion.

Design outcomes

Primary

Measure	Time frame
1) Anti-Ig levels in blood 2) T-cell response in peripheral blood 3) Phenotypes of immune cells in peripheral blood	—

Contacts

Public ContactYoko Hamazaki

Center for iPS Cell Research and Application, Kyoto University

yoko.hamazaki@cira.kyoto-u.ac.jp+81-753667327

Outcome results