FIbrosis Biomarker Mirroring Atrial fibRillation severity as a Key of aging (FIB-MARK) study

FIbrosis Biomarker Mirroring Atrial fibRillation severity as a Key of aging (FIB-MARK) study - FIB-MARK study

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1050200007

Enrollment

250

Registered

2020-04-27

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation atrial fibrillation, rosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) AF patients (receivinf voltage mapping during catheter ablation procedure in phase 1) 2) 20-90 years old 3)Patients who can follow beyond one year

Exclusion criteria

Exclusion criteria: 1)Acute infection or intake of steroids 2)Invasive therapy within 3 months before procedure 3)Those with renal (estimated glomerular filtration ratio <30 ml/min/1.73m2) 4)Those with hepatic impairment 5)Those who previously received catheter ablation or MAZE procedure for AF 6)Inability to adhere to the study procedures.

Design outcomes

Primary

Measure	Time frame
The correlation between inflammatory biomarkers and fibrosis	—

Secondary

Measure	Time frame
The change of serum Inflammatory biomarkers The correlation between the inflammatory biomarkers and recurrent atrial tacyacrrhythmias The correlation between the inflammatory biomarkers and clinical outcomes (death, heart failure, and stroke)	—

Contacts

Public ContactTetsuma Kawaji

Kyoto University Graduate School of Medicine

kawaji@kuhp.kyoto-u.ac.jp+81-75-751-3299

Outcome results