Colorectal Cancer
Conditions
Interventions
Perform thrombosis prevention using intermittent pneumatic compression from during surgery until the patient starts walking postoperatively.
Sponsors
Shiomi Akio
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Planned radical robotic-assisted colorectal surgery for clinical stage I-IV colorectal cancer (2) Aged>=40 years of age. (3) Performance status (PS) of 0-1 according to ECOG criteria (4) No severe organ disorder (bone marrow, lung, kidney, etc.) (5) No deep vein thrombosis on lower extremity venous ultrasonography before enrollment (6) Obtained written informed consent
Exclusion criteria
Exclusion criteria: (1) Planning lateral dissection, surgery for multiple cancers, or combined resection of other organs (2) Contraindication to IPC (3) Requires continued anticoagulation therapy for co-morbidities during surgery (4) Highest-risk patients in the Japanese Guidelines for Prevention of Venous Thromboembolism. (5) Pregnant or lactating women (6) Patients with psychosis, psychiatric symptoms, or dementia that would make it difficult for them to participate in the study (7) Other patients deemed unsuitable for safe conduct of the study by the physician in charge or others
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of asymptomatic or symptomatic VTE within 7 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of symptomatic VTE within 30 days after surgery Incidence of PE within 30 days after surgery Incidence of complications within 30 days after surgery Relation between postoperative step count and asymptomatic VTE Risk factors for asymptomatic or symptomatic VTE Incidence of elevated liver transaminases on postoperative day 7 Incidence of adverse events associated with the use of IPC | — |
Contacts
Public ContactYusuke Yatabe
Shizuoka Cancer Center
Outcome results
None listed