Chronic kidney disease chronic kidney disease
Conditions
Interventions
The starting date of salt reduction instruction at the insurance pharmacy shall be Day 1 and shall continue until Day 84. The salt reduction instruction is given at each visit to the insurance pharmac
D018529
salt resriction
Sponsors
Murata Tomohiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ) Disease name and diagnosis: Patients with eGFR less than 60 mL/min/1.73 m2. 2) Stage and type of disease: CKD severity classification G3a or higher 3) Age: 18 years and older 4) Indicators of systemic status: any 5) Relevant major organ function: kidney 6) Documented patient consent: required
Exclusion criteria
Exclusion criteria: 1) Inability to continuously record blood pressure at home upon waking (or in the morning) 2) Unable to visit the insurance pharmacy of the collaborating institution for 3 months 3) Difficulty in communication 4) Patient is on maintenance dialysis 5) Receives medication on a refill prescription 6) Waking (or morning) blood pressure below 90/60 mmHg or dizziness due to low blood pressure 7) Taking salt as a prescription medication 8) Persons who are considered by the principal investigator or research associate to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salt sensitivity with Solseve before and after intervention: mean of 6 levels of Solseve taste index 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, and 1.6%. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. salt sensitivity by SolSave : percentage of improvement of 0.2% or more of 6 levels of SolSave taste index 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, and 1.6%. 2. estimated salt intake calculated from urine at any time 3. average blood pressure upon waking (or in the morning) during the week 4. survey of patients' attitudes toward salt reduction 5. eGFR 6. urinary protein 7. variation in serum Na concentration 8. variation of serum K concentration 9. variation of hemoglobin level | — |
Countries
Japan, non
Contacts
Public ContactYuki Asai
Mie University hospital
Outcome results
None listed