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Thalamic SEEG

Stereoelectroencephalography studies on thalamic nerve activity and epileptic networks

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1042240024
Enrollment
30
Registered
2024-05-09
Start date
2024-05-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

The design of this study involves a stereotactic intracranial electroencephalography intervention for the thalamus, which has not been commonly performed.

Sponsors

Tomotaka Ishizaki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age 18 years or older Drug-resistant epilepsy Scheduled standard surgical treatment for the purpose of epilepsy surgery Need and scheduled SEEG test for surgical treatment Able to understand the explanation of the study by him/herself and sign the consent form

Exclusion criteria

Exclusion criteria: Patients under 18 years of age Patients with obvious cognitive decline Patients who do not meet the indications for standard epilepsy surgical treatment

Design outcomes

Primary

MeasureTime frame
As evaluation outcomes, the primary endpoints are epileptic neural activity specifically observed in the thalamus before and after an epileptic seizure (waveforms, frequency, and symptomatology during seizures and interictal EEG, functional connectivity between electrodes, and EI for each electrode).

Secondary

MeasureTime frame
Secondary endpoints included thalamic activity at rest, thalamic activity during task loading, procedure performed, seizure prognosis, pre- and postoperative higher brain function, and radiological imaging.

Contacts

Public ContactIshizaki Tomotaka

Nagoya University Hospital, Tokai National Higher Education and Research System

ishizaki.tomotaka.d8@f.mail.nagoya-u.ac.jp+81-52-744-2353

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026