Esophageal atresia, imperforate anus, duodenal atresia, diaphragmatic hernia, etc.
Conditions
Interventions
Comparison of starting TPN within 24 hours vs. after 7 days post-surgery.
Sponsors
Sato Yoshiaki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Neonates scheduled to undergo gastrointestinal surgery within the first month of life. 2) Cases scheduled for postoperative total parenteral nutrition (TPN).
Exclusion criteria
Exclusion criteria: Cases in which TPN cannot be used due to liver dysfunction (prolonged INR > 1.5 with the presence of hepatic encephalopathy, or INR > 2.0, both involving acute liver synthetic failure not corrected by vitamin K administration) or metabolic disorders (clinical symptoms or laboratory findings suggestive of inborn errors of metabolism). Other cases deemed inappropriate by the attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of infectious diseases requiring antibiotic administration within 30 days postoperatively, other than perioperative prophylactic antibiotics. | — |
Secondary
| Measure | Time frame |
|---|---|
| the duration of mechanical ventilation, length of hospital stay, physical growth rates, and neurodevelopmental test results at 18 months of age.etc | — |
Contacts
Public ContactNao Takami
Department of Pediatrics and Neonatology, Nagoya University Graduate School of Medicine
Outcome results
None listed