Diseases that require lumbar puncture Lumber Puncture, Pediatric Anesthesia
Conditions
Interventions
Research participants undergoing lumbar puncture will have a lidocaine-prilocaine cream applied in combination with Intravenous anesthetics.
D000077442
Sponsors
Makino Risa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following inclusion criteria will be eligible for participation: 1. Patients aged 5 to 18 years. 2. Patients who have undergone at least one lumbar puncture in the past. 3. Patients who are scheduled to undergo two or more lumbar punctures. 4. Patients from whom informed consent has been obtained, as evidenced by the signature of the patient or their legally authorized representative on the consent form.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following exclusion criteria will be excluded from the study: 1. Patients with a history of allergy to midazolam or ketamine hydrochloride. 2. Patients with a past history of contact dermatitis caused by topical medications. 3. Patients with skin abnormalities at the study drug application site that may affect observation. 4. Patients who have difficulty expressing their own intentions. 5. Patients deemed unsuitable by the principal investigator or sub-investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total dose of ketamine hydrochloride per body weight | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of midazolam per body weight Presence or absence of difficult movements during lumbar puncture Presence or absence of nausea after the procedure Participant satisfaction Guardian satisfaction Adverse events | — |
Contacts
Public ContactRisa Makino
Hamamatsu University Hospital
Outcome results
None listed