Increase in satiety (decrease in hunger), enhancement in positive affect Healthy Volunteers
Conditions
Interventions
Oral administration of either 140mL aqueous Allulose (10g) and GABA (150mg) solution, 140mL queous Allulose (10g) solution, and 140mL Glucose (10g) solution, and 150mL Water
D000284, D005947, C003243, D005680
Administration Oral, Glucose, psicose (allulose), gamma-Aminobutyric Acid
Sponsors
Homma Shogo
Ohira Hideki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy undergraduate and graduate students Aged 20-39 years Right handed Male Able to communicate fluently in Japanese Willing to participate, with sufficient understanding of the study contents, and able to provide written informed consent
Exclusion criteria
Exclusion criteria: Individuals who have a conflict of interest with the principal investigator or research collaborators (e.g., supervised graduate students, students currently enrolled in their classes) Current illness requiring medication Diagnosis of diabetes mellitus History of psychiatric or neurological disorders Presence of dermatological disorders History of neurosurgical procedures Current use of oral steroids Severe hepatic disease Severe infectious disease Perioperative status (before or after surgery) Severe trauma Dehydration Excessive alcohol consumption Malnutrition Starvation state General debilitation Pituitary insufficiency Adrenal insufficiency History of small intestine resection Presence of atrial fibrillation Body mass index (BMI) more than 25 Fasting blood glucose level more than 110 mg/dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalography (EEG), Electrocardiography (ECG), Electrogastrography (EGG), Respiration, Continuous blood pressure, Pupil diameter, Subjective ratings (satiety, hunger, emotional valence, arousal), Blood glucose level, Responses in the heartbeat counting task, Responses in the craving (preference rating) task | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaire responses: Multidimensional Assessment of Interoceptive Awareness (MAIA), Body Perception Questionnaire - Body Awareness (BPQ-BA), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Ten Item Personality Inventory (TIPI), Dutch Eating Behavior Questionnaire (DEBQ), Original questionnaire on dietary habits, Age, height, weight, Interview (physical and emotional changes during the experiment), Experience sampling method | — |
Contacts
Public ContactShogo Homma
Graduate School of Informatics, Nagoya University
Outcome results
None listed