Electromyographic Changes During Total Intravenous Anesthesia and the Effects of Pentazocine

Dose total intravenous anesthesia using remifentanil in combination with propofol affect bispectral index monitoring resulting from electromyogram interminglement?: The role of pentazocine in the derangement - EMG-BIS Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1041250085

Enrollment

Registered

2025-08-27

Start date

2025-08-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing spinal surgery with the use of motor evoked potentials (MEP) MEP

Interventions

Presence or absence of pentazocine administration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 18 years or older undergoing spinal surgery

Exclusion criteria

Exclusion criteria: Patients with psychiatric disorders, those receiving sedative medications, individuals who did not provide informed consent, patients with known allergies to the study drugs, and those not undergoing total intravenous anesthesia (TIVA)

Design outcomes

Primary

Measure	Time frame
MG values as displayed on the BIS monito	—

Secondary

Measure	Time frame
Bispectral Index (BIS) values, time to awakening, and pain assessment upon return to the ward using the Visual Analog Scale (VAS)	—

Contacts

Public Contactshingo kawashima

Department of Anesthesiology, Seirei Mikatahara General Hospital

shingogo@hama-med.ac.jp+81-53-436-1251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026