Osteoarthritis of the knee
Conditions
Interventions
Wearing insoles for 1 month
Sponsors
Nakase Junsuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients between 40 and 80 years old diagnosed with primary knee OA by X-ray evaluation 2) Patients who are able to exercise on a treadmill (3) Patients who have given their free and voluntary written consent to participate in this study after obtaining sufficient informed consent.
Exclusion criteria
Exclusion criteria: 1 Persons who have been diagnosed with diabetes mellitus and are under treatment, or who have an HbA1c of 6.5 percent or higher without treatment. 2 Patients with a history of medical disease (e.g., heart failure) who should avoid exercise 3 Patients with complaints in the lower limbs except knee joint pain 4 Patients with a history of allergy to the drug (18F-FDG) after undergoing a PET scan in the past 5 Subjects who are deemed inappropriate as research subjects by the principal investigator or subinvestigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in 18F-FDG accumulation (SUV) in the popliteal muscles of the knee joint on PET images before and after insole prescription | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in skeletal muscle accumulation on PET images before and after insole prescription: thigh, lower leg, and foot Change in pain (VAS) before and after insole prescription Change in moment of internal knee rotation before and after insole prescription | — |
Contacts
Public ContactYasushi Takata
13-1, Takaramachi, Kanazawa city
Outcome results
None listed