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A Study on Intake Methods of Polyethylene Glycol Formulation for Constipation Treatment Focused on Improving Palatability

An Exploratory Study on Intake Methods of Polyethylene Glycol Formulation for Constipation Treatment Focused on Improving Palatability

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1041240066
Enrollment
35
Registered
2024-08-01
Start date
2024-07-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

palatability

Interventions

The test sample (MOVICOL Combination Powder LD + organoleptic masking agents) is dissolved in 10 mL of water. The solution is held in the mouth for 10 seconds and then spit out. After spitting out, vo

Sponsors

Tatsuguchi Mariko
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy volunteers, 18 years of age or older (both male and female)

Exclusion criteria

Exclusion criteria: 1. Volunteers with obvious taste disorders 2. Volunteers with self-reported oral abnormalities such as stomatitis 3. Volunteers with a history of allergy to the ingredients of Movicol oral powder 4. Volunteers with confirmed or suspected diseases for which Movicol oral powder is contraindicated (intestinal obstruction, intestinal perforation, severe inflammatory bowel disease such as ulcerative colitis, Crohn's disease, or toxic megacolon) 5. Volunteers who are pregnant, possibly pregnant, or breastfeeding 6. Any other volunteers deemed inappropriate by the principal investigator or co-investigators

Design outcomes

Primary

MeasureTime frame
VAS score of overall palatability

Secondary

MeasureTime frame
VAS score of bitterness, VAS score of sweetness, VAS score of sourness, VAS score of saltiness, VAS score of smell and recommendation for children to take

Contacts

Public ContactMariko Tatsuguchi

Hamamatsu University School of Medicine

marikot@hama-med.ac.jp+81-53-435-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026