Mild cognitive impairment Cognitive decline, Alzheimers disease
Conditions
Interventions
Matcha 1.5g stick: Drink 1 cup per day, dissolved in water or hot water, before or between meals.
Barley tea 0.8g stick: Dissolve in water or hot water and drink 1 cup per day, before or between meal
D013662
Matcha, Barley tea, tea
Sponsors
Ono Kenjiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individuals who visit Kanazawa University Hospital Neurology Outpatient Department 2) Men and women aged 50 to under 90 on the date of consent 3) Score of Montreal cognitive assessment Japanese version (MoCAJ) is 25 points or less 4) Individuals who can consume matcha or barley tea and be able to record the consumption. 5) Individuals who agree not to make extreme lifestyle changes such as exercise habits or eating habits while participating in the study. 6) Individuals who have obtained sufficient informed consent and written consent of the subject's own free will to participate in the research.
Exclusion criteria
Exclusion criteria: 1) Individuals who have a history of allergies to matcha or barley tea 2) People who have a habit of drinking matcha or barley tea every day 3) Individuals who have the habit of consuming large amounts of tea (any type) every day (approximately 10 cups, 2000ml or more) 4) Individuals who are taking warfarin 5) People with dementia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive assessment Japanese version (MoCA-J) score change: MoCA-J score change from screening 24 weeks after intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in NouKNOW, Minimental state examination Japanese version (MMSE-J), DASC-21 score, cerebral white matter lesions and brain volume (global, regional) on head MRI 24 weeks after intake Amount of change, relationship between changes in intestinal flora from baseline after 24 weeks of intake and cognitive function | — |
Contacts
Public ContactMoeko Shinohara
Kanazawa University Hospital
Outcome results
None listed