Metabolic changes by niacin

Study of metabolite changes by niacin-related supplements on healthy subjects - Niacin metabolism

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1041230130

Enrollment

Registered

2024-01-11

Start date

2024-01-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects None

Interventions

Taking supplements 1) NMN250mg 2) NMN125mg 3) Nicotinamide 250mg 4) Nicotinic acid 50mg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Healthy subjects 2) Young adults (18 to 29 years of age) and middle-aged and older adults (50 years of age or older) (3) Individuals who have given their free and voluntary written consent to participate in the study after obtaining sufficient informed consent.

Exclusion criteria

Exclusion criteria: (1) Pregnant, lactating, or possibly pregnant (2) Those taking medicines or supplements containing nicotine, nicotinic acid, or NMN. (3) Those with a history of hypersensitivity to medicines containing nicotine, nicotinic acid, or NMN, or to various foods containing nicotine, nicotinic acid, or NMN supplements. (4) Those who are deemed inappropriate as research subjects by the Principal Investigator for other reasons.

Design outcomes

Primary

Measure	Time frame
Change in urinary metabolite levels after taking supplements	—

Secondary

Measure	Time frame
Change in bood metabolite levels after taking supplements	—

Contacts

Public ContactAtsushi Hirao

Kanazawa University

ahirao@staff.kanazawa-u.ac.jp+81-76-264-6755

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026