Spinal diseases Spinal
Conditions
Interventions
Begin general anesthesia with sevoflurane (5-8% end expiratory concentration) and laughing gas (40% concentration mixed with oxygen). After the patient is asleep, a peripheral venous tract is secured
randomized controlled trial
Sponsors
Kojima Taiki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Spinal surgery patients scheduled for intraoperative MEP less than 1 year old
Exclusion criteria
Exclusion criteria: Patients with preoperative lower limb motor dysfunction (incomplete or complete paralysis) Patients who should refrain from using inhalation anesthetics (sevoflurane) (e.g., neuromuscular disease, history (including suspicion) of malignant hyperthermia) Patients who cannot use propofol (e.g., egg white allergy) Patient and family refusal for any reason Intraoperative circulatory instability due to anesthetics administered by intraoperative intervention If the anesthesiologist in charge (independent of the research team) determines that the protocol anesthetic agents do not provide adequate depth of anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage (%) of attenuation of the TOP to BOTTOM values of the MEP potential waveform (continuous variable) in the upper extrimities. | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage (%) of attenuation of the TOP to BOTTOM values of the MEP potential waveform (continuous variable) in the lower extrimities. | — |
Contacts
Public ContactTaiki Kojima
Aichi Children Health and Medical Center
Outcome results
None listed