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Effect of combination of basic fibroblast growth factor and heparin on skin graft donor site healing

Effect of topical treatment with a combination of basic fibroblast growth factor and heparin on skin graft donor site healing: a randomized controlled pilot study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1041230082
Enrollment
12
Registered
2023-09-27
Start date
2020-08-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Split-thickness skin graft harvesting wound with dermatome Skin Graft Harvest, Donor Site, Wound Healing

Interventions

Patients are randomly allocated to either the control or intervention group at a 1:1 ratio before surgery. All STSGs are harvested from the lateral thigh at a depth of 12/1000 inches using an air-powe
D009824
basic Fibroblast Growth Factor (bFGF), Heparin, Ointment

Sponsors

Kohyama Keishi
Lead Sponsor
Okada Hideshi
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Underwent split-thickness skin graft (STSG) harvesting from the thigh for reconstructive surgery Aged 20 >= years who signed an informed consent form Provide written consent for participation in this study from the individual or a legal representative

Exclusion criteria

Exclusion criteria: Showed bleeding tendencies Deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
Epithelialized area (or wound area) of skin harvested site at 4 weeks postoperatively

Secondary

MeasureTime frame
1, Epithelialized area (or wound area) of skin harvested site at 4, 7,11,14,18, 21, 25, and 28 days postoperatively (the number of days required for complete epithelialization) 2, Epithelialized area (or wound area) variation of skin harvested site at 4, 7,11,14,18, 21, 25, and 28 days postoperatively 3, Relationship of patient characteristics and blood test results with the epithelialization

Contacts

Public ContactKeishi Kohyama

Gifu University Graduate School of Medicine

casey_cybercat@yahoo.co.jp+81-58-230-6000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026