Healthy adult: Predict complications such as airway obstruction under sedation
Conditions
Interventions
After measuring control values, administer a continuous dose (Target control infusion:1.5) of propofol.
Trial A:Observe for 15 minutes during propofol administration.
Trial B:Perform 15 minutes of ora
Sponsors
Hayashi Shintaro
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male 2. 20 to 39 old over 3. American Society of Anesthesiologist Physical Status Classification(ASA PS) 1-2 4. BMI less than 30 5. Patients who understand the contents of this study and are willing to provide written informed consent for participation in this study
Exclusion criteria
Exclusion criteria: 1. ASA PS 3 over 2. Patients with a history of hypersensitivity to propofol 3. Medicine users 4. Person who the research director judged inappropriate as a research subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Perfusion Index (PI) due to differences in sedative dose / maintenance dose | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bispectral Index(BIS value) 2. Modified observer assessment of alertness / sedation scale(MOAA/S) 3. SpO2, EtCO2, respiratory rate 4. blood pressure, pulse rate | — |
Contacts
Public ContactShintaro Hayashi
Asahi University
Outcome results
None listed