Colorectal cancer Colorectal cancer
Conditions
Interventions
This study evaluates wound closure techniques using a 2x2 factorial design, comparing subcutaneous suturing (with vs without) and fascial closure methods (continuous vs interrupted) in laparoscopic or
Surgery
Subcutaneous suturing
Fascial closure
Sponsors
Matsuhashi Nobuhisa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients aged >=18 years with colorectal cancer who are scheduled to undergo laparoscopic or robot-assisted resection (with a mini-laparotomy via a midline or Pfannenstiel incision). - Patients in whom wound closure can be performed according to the study protocol. - Patients who have received a full explanation of the study and have provided written informed consent.
Exclusion criteria
Exclusion criteria: - Patients diagnosed with colorectal cancer accompanied by bowel obstruction who are judged to require emergency or urgent surgery, those requiring preoperative colonic stent placement, or those considered unsuitable for standard mechanical bowel preparation. - Patients scheduled for placement of prosthetic material (e.g., immediate mesh implantation) at the same incision site. - Patients with severe active infection or immunocompromised conditions (e.g., severe neutropenia). - Pregnant women or those with a high possibility of pregnancy. - Patients in whom standardization of the study procedures is considered difficult (e.g., inability to adhere to the protocol in emergency surgery). - Patients judged to be inappropriate for inclusion in the study by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of superficial incisional surgical site infection (SSI) within 30 days postoperatively, defined according to CDC criteria, with an ASEPSIS score >20 considered as confirmed SSI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of incisional hernia at 12 and 24 months postoperatively, assessed by abdominal CT and clinical examination. | — |
Contacts
Public ContactKeita Matsumoto
Department of Gastroenterological Surgery, Gifu University Hospital
Outcome results
None listed