None None
Conditions
Interventions
Nicotinamide
Sponsors
Hirao Atsushi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Habitual drinkers 1) Healthy individuals (men and women aged 40 years or older who do not suffer from any medical conditions requiring prescription medications). 2) Habitual drinkers (those who consume alcohol on three or more days per week, with a daily pure alcohol intake of 20g or more for men and 20g or more for women). 3) Individuals who can provide information regarding their usual alcohol consumption, including type, quantity, and frequency. 4) Individuals who have undergone a health checkup within the past year and can provide relevant information. 5) Individuals who have provided written consent based on their free will after receiving sufficient informed consent regarding participation in this study. Regular drinker (drinks at least once a week) 1) Healthy individuals (men and women aged 30 years or older who do not suffer from any medical conditions requiring prescription medications). 2) Habitual drinkers (those who consume alcohol on one or more days per week). 3) Individuals who can provide information regarding their usual alcohol consumption, including type, quantity, and frequency. 4) Individuals who have undergone a health checkup within the past year and can provide relevant information. 5) Individuals who have provided written consent based on their free will after receiving sufficient informed consent regarding participation in this study.
Exclusion criteria
Exclusion criteria: 1) Individuals who are pregnant, breastfeeding, or may be pregnant. 2) Individuals who regularly consume medications or food products, including supplements, containing nicotinamide, nicotinic acid, NMN, or nicotinamide riboside (NR). However, those who have discontinued use at least five days before the study initiation may be eligible for participation, provided that the name of the medication or supplement and the date of discontinuation are recorded. 3) Individuals with a history of hypersensitivity to medications or food products containing nicotinamide, nicotinic acid, NMN, or NR. 4) Individuals who contract any illness during the study period. 5) Individuals deemed unsuitable for participation by the principal investigator or co-investigators for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chenge in blood metabolite levels after taking supplement | — |
Secondary
| Measure | Time frame |
|---|---|
| Chenge in urinary metabolite levels after taking supplement | — |
Contacts
Public ContactAtsushi Hirao
Kanazawa University
Outcome results
None listed