Diseases requiring noncardiac major surgery
Conditions
Interventions
None listed
Sponsors
Nakanishi Toshiyuki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Men and women aged 45 or older 2) Patients scheduled to undergo esophagectomy, hepatectomy, biliary surgery, pancreatectomy, abdominal aortic replacement, total cystectomy, or adrenalectomy 3) Patients with an ASA-PS (American Society of Anesthesiologists physical status) of 1 to 4. 4) Patients who have provided written informed consent
Exclusion criteria
Exclusion criteria: 1) Patients who are pregnant or suspected of being pregnant 2) Patients whose will cannot be confirmed 3) Patients on dialysis 4) Patients with a serum creatinine level of >= 4.0 mg/dL at least once within 3 months prior to surgery 5) Patients who have had acute kidney disease, cerebral infarction, cerebral hemorrhage, transient ischemic attack, acute myocardial infarction, angina pectoris, or acute heart failure (including acute exacerbation of chronic heart failure) within 30 days prior to surgery 6) Patients on mechanical ventilation with tracheal intubation prior to surgery 7) Patients receiving continuous intravenous inotropic or vasoconstrictive agents prior to surgery 8) Patients with preoperative shock vital signs 9) Patients with incomplete or erroneous data to be analyzed 10) Patients undergoing emergency surgery 11) Patients who have been the subject of this study in the past 12) Patients who are deemed by the investigators to be unsuitable for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A composite outcome consisting of acute kidney injury or myocardial injury within 7 days postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute kidney injury (AKI) within 7 days after surgery Acute kidney disease (AKD) and chronic kidney disease (CKD) after surgery Myocardial injury within 7 days and within 30 days after surgery Postoperative cognitive dysfunction Postoperative delirium Resuscitated cardiac arrest within 30 days after surgery Major cardiovascular event within 30 days after surgery Cerebrovascular complications within 30 days after surgery New-onset atrial fibrillation within 30 days after surgery (with symptoms of hypotension, angina, heart failure, or requiring drug therapy or defibrillation) Unexpected postoperative intensive care unit admission Postoperative renal replacement therapy Death from any cause within 7 days, 30 days, 90 days, 1 year after surgery Post-anesthesia care unit (PACU) length of stay Postoperative hospital stay | — |
Contacts
Public ContactToshiyuki Nakanishi
Nagoya City University Graduate School of Medical Sciences
Outcome results
None listed