A Comparative Study of New and Existing Evaluation Methods for Cerebral Circulatory Impairment after Subarachnoid Hemorrhage

Clinical trial comparing cutaneous sympathetic nerve activity and existing medical indexes for cerebral circulatory disturbance after subarachnoid hemorrhage - SAH_SKNA

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1040240114

Enrollment

Registered

2024-10-29

Start date

2024-10-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid hemorrhage Subarachnoid hemorrhage, Skin sympathetic nerve activity, delay cerebral inferction

Interventions

Measuring Cutaneous Sympathetic Nerve Activity In this study, in order to keep the analysis conditions constant, skin sympathetic nerve activity information is obtained while the patient is in a supin

Skin sympathetic nerve activity

Eligibility

Inclusion criteria

Inclusion criteria: Disease name and diagnosis: subarachnoid hemorrhage, diagnosed by imaging (CT, MRI, angiography) Age: 20 years and older Gender: any Severity of subarachnoid hemorrhage: any Written patient consent: if it is difficult to obtain consent, a person who can obtain consent from a surrogate, such as a family member

Exclusion criteria

Exclusion criteria: Relevant major organ function: cases with poor general condition such as severe cardiac disease, takotsubo cardiomyopathy, septic shock, etc. Cases of subarachnoid hemorrhage with findings of spinal cord consolidation related to autonomic nervous system regulation Patients who are deemed inappropriate as research subjects by the principal investigator or research coordinator (e.g., subarachnoid hemorrhage due to rupture of dissecting aneurysm, subarachnoid hemorrhage due to rupture of infected aneurysm, and cases diagnosed as having a unique course of subarachnoid hemorrhage, such as traumatic subarachnoid hemorrhage).

Design outcomes

Primary

Measure	Time frame
Delayed cerebral ischemia or stroke up to 14 days after onset of subarachnoid hemorrhage.	—

Secondary

Measure	Time frame
Glasgow Coma Scale (GCS) on day 14 after onset of subarachnoid hemorrhage Modified Rankin Scale (mRS) at the time of discharge Cerebral vascular flow velocity (measured by TCD) Degree of intracranial vascular stenosis (as measured by CT, MRI, cerebral angiography) Laboratory tests of medical course (severity of subarachnoid hemorrhage, fluid balance (estimated by volume of rehydration fluid + fluid intake - urine volume), body weight, TCD, blood collection (electrolytes, IL-10))	—

Measure

Time frame

Glasgow Coma Scale (GCS) on day 14 after onset of subarachnoid hemorrhage Modified Rankin Scale (mRS) at the time of discharge Cerebral vascular flow velocity (measured by TCD) Degree of intracranial vascular stenosis (as measured by CT, MRI, cerebral angiography) Laboratory tests of medical course (severity of subarachnoid hemorrhage, fluid balance (estimated by volume of rehydration fluid + fluid intake - urine volume), body weight, TCD, blood collection (electrolytes, IL-10))

—

Contacts

Public ContactSho Tamai

Kanazawa universty

sho.tamai@med.kanazawa-u.ac.jp+81-76-265-2384

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026