defecation disorders rectal cancer, postoperative, low anterior resection syndrome
Conditions
Interventions
Intervention group: The intervention group receive instruction on pelvic floor rehabilitation and start rehabilitation one week before rectal cancer surgery. The intervention group restarts pelvic flo
Sponsors
Sakata Mayu
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria is patients diagnosed with rectal cancer 10 cm or below from the anal verge and undergoing surgery at the department of surgery, Hamamatsu University Schoolo of medecine, between April 2023 and March 2028.
Exclusion criteria
Exclusion criteria: 1. patients who are scheduled to undergo colostomy in addition to resection of the primary tumor 2. patietns who are difficluty preserving anorectal function by resection of the primary tumor 3. patients who have undergone preoperative treatment (chemotherapy, radiation therapy, or radiation chemotherapy) related to the primary tumor 4. patients with neuromuscular diseases 5. patients with respiratory dysfunction requiring preoperative respiratory rehabilitation 6. pregnant or potentially pregnant women 7. women who are breast-feeding 8. patients determined ineligible for the study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of patients with low anterior resection syndrome score of 30 or more points at 3 months postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Defecation function evaluatated 1 week before surgery and 1, 3, 6, 9, and 12 months after surgery. (Defecation dysfunction is evaluated by intra-anal pressure measurement (functional anal canal length, maximum resting pressure, and maximum squeeze pressure), St. Marks score, LARS score, and mFIQL.) The rate of performance of pelvic floor rehabilitation. Association between the rate of performance of pelvic floor rehabilitation at 3 and 6 months preoperatively and improvement in defecation function. The rate of patients receiving postoperative drug therapy for defecation disorders. Adverse events due to pelvic floor rehabilitation. | — |
Contacts
Public ContactTadahiro Kojima
Hamamatsu University School of Medecine
Outcome results
None listed