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Development of a novel antimicrobial strategy during pancreatoduodenectomy

Development of proactive antimicrobial strategy using novel rapid test complex for microorganisms during pancreatoduodenectomy - DOREMI trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1040230010
Enrollment
150
Registered
2023-04-19
Start date
2022-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatoduodenectomy pancreatoduodenectomy

Interventions

For the intervention group, a combined test (RMiX) of the following i-iii will be performed Tmm method: PCR of DNA from body fluids is performed to identify and quantify the initiating organisms by th

Sponsors

Fujii Tsutomu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients are scheduled to undergo pancreaticoduodenectomy. Patients must be at least 20 years of age at the time of enrollment. ECOG PS status 0, 1, or 2 The patient's consent to participate in this study was obtained.

Exclusion criteria

Exclusion criteria: History of serious drug hypersensitivity or drug allergy. Patients have obvious preoperative infection or inflammation (e.g., fever over 38.0 digree). Patient has a serious underlying disease (cardiac, pulmonary, metabolic, renal, cirrhosis, bowel obstruction, etc.) and is considered by the surgeon to be at high risk (more than 5%) of surgery-related mortality. Patients have dementia, psychosis, or psychiatric symptoms. Other conditions that make them unsuitable for the study as determined by the study investigator(s).

Design outcomes

Primary

MeasureTime frame
RMiX-PAT Treatment compliance rate

Secondary

MeasureTime frame
RMiX Target coverage

Contacts

Public ContactHaruyoshi Tanaka

University of Toyama

tanakaharu@med.nagoya-u.ac.jp+81-76-434-7331

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026