Atopic dermatitis Atopic dermatitis
Conditions
Interventions
Participants in the Soap group wash their skin with soap when bathing or showering for 7-14 days.
Participants in the Mild-Soap group wash their skin with Mild-Soap when bathing or showering for 7-14
Sponsors
Inuzuka Yusuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients diagnosed with AD based on the UK Working Partys Diagnostic Criteria Patients aged younger than 15 years old at recruitment Patients whose eczema excluding the head, neck, wrists/ankles, and genitals are mild to severe Patients who bathe or shower at least once a day Patients whose caregivers agreed to participate in this study in writing
Exclusion criteria
Exclusion criteria: 1. Patients with skin infection 2. Patients who apply steroid ointment, antihistamine ointment (oral is allowed), NSAIDs ointment, tacrolimus ointment, dergocitinib ointment, and difamilast ointment for diseases other than atopic dermatitis. (It is possible to apply to areas other than the intervention site.) 3. Patients taking cyclosporine, corticosteroids, baricitinib, upadacitinib, or abrocitinib 4. Patients receiving dupilumab or nemolizumab 5. Physicians decide that the patients is not appropriate for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of achievement of EASI100 excluding head and neck at the end of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| EASI score excluding head and neck at the end of the study POEM score at the end of the study Stratum corneum hydration of the forearm at the end of the study Number of occurrences of serious adverse events Adverse events for which a causal relationship to the intervention cannot be denied Presence or absence of contagious impetigo Presence or absence of skin infections other than contagious impetigo Pain during bathing (10-step scale) | — |
Contacts
Public ContactYusuke Inuzuka
Hamamatsu University School of Medicine
Outcome results
None listed