A study to investigate the relationships between exercise and the renin-angiotensin system in the kidney

A prospective study to investigate the exercise in patients with chronic kidney disease reduces renal damage through suppression of the renin-angiotensin system in the kidney

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1040210055

Enrollment

Registered

2021-08-18

Start date

2021-08-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CKD

Interventions

Exercise therapy is performed for 3 mmonths in the outpatient clinic once a week and at home in the remaining 6 days a week.

Exercise

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients over 20 years 2. CKD patients 3. Patients who have undergone total hip arthoplasty 4. Patients who have obtained the consent for this study by signing the consent form.

Exclusion criteria

Exclusion criteria: 1. CKD patients undergoing dialysis or kidney transplantation 2. Patients using immunosuppressants and RAS inhibitors that affect renal damage and renal RAS activity. 3. Patients whose exercise is prohibited due to heart or brain disease

Design outcomes

Primary

Measure	Time frame
Urinary angiotensinogen excretion rate and the change rate of it	—

Secondary

Measure	Time frame
Urinary albumin excretion rate and the change rate of it Urinary protein excretion rate and the change rate of it Number of steps and the change rate of it Calories burned and the change rate of it Muscle strength and the change rate of it Muscle mass and the change rate of it Adverse events	—

Contacts

Public ContactNaro Ohashi

Hamamatsu University School of Medicine

ohashi-n@hama-med.ac.jp+81-534352261

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026