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Comparison of hemodynamic changes between high-flow nasal oxygen therapy and face mask ventilation during anesthetic induction in cardiovascular surgery

Comparison of hemodynamic changes during anesthetic induction with remimazolam high-flow nasal oxygen therapy and face mask ventilation in patients undergoing cardiovascular surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1032260135
Enrollment
60
Registered
2026-05-18
Start date
2026-05-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients aged 70 years or older scheduled to undergo cardiovascular surgery under general anesthesia General Anesthesia

Interventions

Sponsors

Asai Takashi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo cardiovascular surgery under general anesthesia 2. Patients in whom remimazolam is used as the sedative agent for anesthesia induction 3. Patients aged 70 years or older at the time of informed consent 4. Patients with an American Society of Anesthesiologists Physical Status classification of 2 and 3 Class II: Patients with mild to moderate systemic disease Class III: Patients with severe systemic disease 5. Patients who have provided written informed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1. Patients undergoing emergency surgery 2. Patients who may be pregnant 3. Patients with anticipated difficult airway or difficult intubation 4. Patients with a body mass index (BMI) of 35 or higher (kg / m^2 ) 5. Patients with high risk of aspiration 6. Patients with conditions in which carbon dioxide retention is undesirable (e.g., pulmonary hypertension, right heart failure)

Design outcomes

Primary

MeasureTime frame
Incidence of hypotension (defined as a mean arterial pressure < 65 mmHg)

Secondary

MeasureTime frame
Total dose of vasopressors administered during anesthetic induction Incidence of hypoxemia (defined as a oxygen saturation of < 95%)

Contacts

Public ContactReo Uchida

Dokkyo Medical University Saitama Medical Center

r-uchida@dokkyomed.ac.jp+81-48-965-4948

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026