Simple Cognitive Function Assessment Using Near-Infrared Brain Measurement

A New Screening Method for Mild Cognitive Impairment Using Time-Resolved NIRS-Based Brain Atrophy Estimation - TRS-NIRS MCI Screening

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1032250846

Enrollment

Registered

2026-03-26

Start date

2023-12-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suspected mild cognitive impairment Mild cognitive impairment and early-stage dementia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who underwent brain MRI for clinical purposes (2) Patients suspected of having mild cognitive impairment (3) Adults, mainly middle-aged to older individuals at increased risk of dementia (4) Individuals who provided written informed consent after receiving sufficient explanation

Exclusion criteria

Exclusion criteria: (1) Individuals who refused participation in this study (except when anonymized data had already been shared with collaborating institutions) (2) Individuals judged inappropriate by the principal investigator

Design outcomes

Primary

Measure	Time frame
Correlation between brain atrophy and optical path length measured by TRS-NIRS (760 nm, 800 nm, and 830 nm)	—

Secondary

Measure	Time frame
(1) Correlations between TRS-NIRS parameters (mainly oxygen saturation and optical path length) and blood test parameters (2) Correlations between TRS-NIRS / blood test parameters and questionnaire-based assessment scales	—

Contacts

Public ContactKatsunori Oyama

College of Engineering, Nihon University

oyama.katsunori@nihon-u.ac.jp+81-24-956-8830

Outcome results