End-stage kidney disease
Conditions
Interventions
This study is a single-center, prospective, placebo-controlled, double-blind, randomized controlled trial. The procedures are as follows:
1. Informed Consent:
Surgeons A and B, who are co-investigator
SuperLizer
Stellate ganglion block
Sponsors
Ueda Kenichi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are scheduled for arteriovenous fistula creation for hemodialysis. 2. Patients who have a sufficient understanding of the research and provide consent. 3. Patients who are 18 years of age or older at the time of obtaining consent.
Exclusion criteria
Exclusion criteria: 1. Patients with arterial vessel diameter at the planned arteriovenous fistula site of 1.5mm or less. 2. Patients with venous vessel diameter at the planned arteriovenous fistula site of 2mm or less after tourniquet 3. Patients with significant arterial sclerosis at the planned arteriovenous fistula site. 4. Patients with glaucoma. 5. Patients with cataracts. 6. Patients with BMI >= 35. 7. Patients with skin disorders at the planned irradiation site. 8. Patients who are considered unsuitable for participation in this study by the attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the diameter of the radial superficial vein (mm): Measurements are taken before and after irradiation using an ultrasound device. The measurements are performed after applying a manual blood pressure cuff set to 80 mmHg for at least 30 seconds. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Changes in Vascular Diameter (mm) Before and After Irradiation: - For veins, measurements are taken using an ultrasound device after applying a manual blood pressure cuff set to 80 mmHg for at least 30 seconds. - For arteries, no cuff application is required. The specific vessels to be measured include: 1.Radial Artery 2.Communicating Vein (defined as a vein connecting superficial and deep veins in the midline) 3.Median Vein 4.Brachial Artery 2. Immediate Postoperative Shunt Blood Flow and Vascular Diameter: - Measurements (blood flow: mL/s; vascular diameter: mm) are performed using an ultrasound device immediately after shunt creation. 3. Shunt Blood Flow and Vascular Diameter Two Weeks Post-Surgery: - Measurements (blood flow: mL/s; vascular diameter: mm) are performed using an ultrasound device during a routine outpatient visit. 4. Shunt Patency Rates at Two Weeks and Six Months Post-Surgery: - Patency Criteria: 1.If the dialysis shunt is in use and usable, it is considered patent. 2.If the dialysis shunt is not yet in use, patency is assessed comprehensively based on the following: - Auscultation for shunt sounds. - Palpation for shunt thrill. - Ultrasound Confirmation of blood flow. 5. Perioperative Complications: - Document and analyze any complications occurring during the perioperative period. | — |
Contacts
Public ContactZhuan Jin
Kameda Medical Center
Outcome results
None listed