Heart failure with preserved ejection fraction
Conditions
Interventions
1) Exercise stress echocardiography with expired gas analysis
2) Blood sampling from left atrium
Sponsors
Obokata Masaru
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age equal to or more than 20 years old 2) Patients with EF of 50% or >50% 3) Patients with established HFpEF or subjects who are suspected of HFpEF 4) Subjects who are planned to be treated with rhythm control therapy for atrial fibrillation 5) Patients who give written consent to participate in this study
Exclusion criteria
Exclusion criteria: 1) Patients with complications contraindicated for exercise testing (acute decompensated heart failure, history of left ventricular ejection fraction less than 40%, non-group II pulmonary hypertension, more than mild aortic or mitral valve stenosis, more than moderate aortic or mitral valve regurgitation, cardiomyopathy, acute coronary syndrome, complicated adult congenital heart disease) 2) Patients who cannot exercise their legs due to abnormalities in joints, muscles, etc. 3) Patients who are judged to be unsuitable for the study by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in peak oxygen consumption or cardiovascular reserve function during exercise stress echocardiography from baseline to six-month after the rhythm control therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Association between the success of rhythm control therapy and outcomes | — |
Contacts
Public ContactTomonari Harada
Gunma University Hospital
Outcome results
None listed