Depression Depression
Conditions
Interventions
After acute rTMS therapy, maintenance rTMS
therapy will be administered for 12 months:
once a week for the first 6 months and once
every two weeks for the latter 6 months.
Transcranial magnetic stimulation
Sponsors
Hayashi Daisuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who: 1) are aged >=18 and have responded or remitted by acute repetitive transcranial magnetic stimulation (rTMS) therapy conducted in accordance with the guidelines for the proper use of rTMS 2) are willing to adhere to the treatment schedule if the patients wish to receive maintenance rTMS therapy
Exclusion criteria
Exclusion criteria: Those who: 1) are in pregnancy 2) have significant suicidal ideation (HAMD17 suicide item score of 3 or higher) 3) experienced serious adverse events during acute rTMS therapy 4) are deemded inappropriate to participate by judgement of principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rates of relapse/recurrence up to 12 months after enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) relapse/recurrence rates at 3, 6, and 9 months after enrollment (subjects who relapsed/recurred prior to each assessment period will be treated as relapsing /recurring thereafter.) 2) response rates at 3, 6, 9, and 12 months after enrollment 3) remission rates at 3, 6, 9, and 12 months after enrollment 4) change in the scores of HAMD17, MADRS, QIDS, and PHQ-9 after enrollment 5) period from enrollment until relapse /recurrence 6) adverse events 7) malfunction | — |
Contacts
Public ContactNemoto Kazuki
Satt Co., Ltd
Outcome results
None listed