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PD&ARNI

Effects of sacubitril-valsartan on cardiac function and body fluid volume in peritoneal dialysis patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1031250108
Enrollment
20
Registered
2025-05-19
Start date
2025-05-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease G5D Peritoneal dialysis patient with hypertension

Interventions

Oral administration of sacubitril valsartan

Sponsors

Osano Keiichi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria will be included. 1. Adult patients, regardless of gender, who visit the Department of Nephrology at Yamanashi University Hospital and have been undergoing peritoneal dialysis for at least six months. 2. Peritoneal dialysis patients with hypertension. 3. Patients who can provide written informed consent to participate in this study. Consent must be given by the individual.

Exclusion criteria

Exclusion criteria: 1.Patients who meet the contraindications for sacubitril valsartan 2.Patients who were taking sacubitril valsartan before enrollment in the study 3.If a doctor determines that the person is unsuitable for the program

Design outcomes

Primary

MeasureTime frame
Changes in LVEF 3 and 6 months after taking Sacubitril Valsartan compared to before administration

Contacts

Public ContactKeiichi Osano

University of Yamanashi Hospital

kosano@yamanashi.ac.jp+81-552732288

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026