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Analysis of the Therapeutic Effects of Chinese Herbal Medicines on Periodontal Disease

Analysis of the Therapeutic Effects of Chinese Herbal Medicines on Periodontal Disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1031250072
Enrollment
40
Registered
2025-04-30
Start date
2024-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease Periodontal disease, Chinese herbal medicine, Kampo

Interventions

In patients 20 years of age or older who require treatment for periodontal disease, the following three groups of therapeutic agents will be administered for one week. Group 1: Antibiotics (Zithromax

Sponsors

Reiko Aizawa
Lead Sponsor
Asai Masashi
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Men and women over 20 years of age who come to Reina Dental and need treatment for periodontal disease.

Exclusion criteria

Exclusion criteria: Patients with severe periodontal disease (periodontal pockets >7 mm and tooth mobility >2 mm) requiring surgical treatment should be excluded.

Design outcomes

Primary

MeasureTime frame
1. The clinical symptoms in the oral cavity are divided into four levels: severe, moderate, mild, and none, with the degree of spontaneous pain, tenderness, redness, swelling, bleeding, drainage, and tooth movement being scored as 3, 2, 1, and 0 points for each level, and the total score is used to evaluate the condition before treatment. 2. Periodontal pocket depth is evaluated as follows: 0 to 2 mm: normal; 3 mm: gingivitis P1; 4-6 mm: moderate periodontitis P2; 7 mm or more: severe periodontitis P3. 3. Quantification of periodontal bacteria: After bacteria are collected from periodontal pockets, bacteria counts are quantified using an Orcore oral bacteria detection device.

Contacts

Public ContactAsai Masashi

Yokohama University of Pharmacy

masashi.asai@yok.hamayaku.ac.jp+81-45-859-1300

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026