Healthy subjects
Conditions
Interventions
Sponsors
Taida Takashi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects who have not undergone upper or lower gastrointestinal surgery. 2) Male subjects who are over 20 years old and under 50 years old at the time of consent. 3) Subjects who have been fully informed of the study and who have given their consent in writing of their own free will with full understanding.
Exclusion criteria
Exclusion criteria: 1) Subjects who have received other laxatives within 1 week prior to the start of laxative administration 2) Subjects who are at risk of shock, anaphylaxis after receiving laxatives. 3) Subjects with suspected intestinal obstruction or severe constipation. 4) Subjects with diarrhea or bloody stool. 5) Female participants who are pregnant, planning a pregnancy or breastfeeding. 6)Other subjects who are judged by the investigator or subinvestigator to be unsuitable for the safe conduct of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total IgA in bowel lavage fractions 1-2 after laxative administration | — |
Secondary
| Measure | Time frame |
|---|---|
| -To measure IgG and IgM in intestinal lavage fluid fractions 1-2 after laxative administration -CTB-specific IgA -Total protein level of the above -Physical properties of multimeric IgA | — |
Contacts
Public ContactTakashi Taida
Chiba University Hospital
Outcome results
None listed