Diseases for which therapeutic thoracoscopic partial lung resection is indicated spontaneous pneumothorax, metastatic lung tumors, and primary lung cancer
Conditions
Interventions
Patients undergoing thoracoscopic surgery will be randomly assigned to two groups: one receiving intercostal nerve block at the beginning of the surgery, and the other receiving it before wound closur
Intercostal nerve block, pre-emptive analgesia
Sponsors
Ichimura Hideo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients scheduled for thoracoscopic partial lung resection using only a port (surgical approach without the assumption of using a utility window) Age: 16 years or older and younger than 80 years at the time of consent acquisition ASA-PS: 1-3 Patients who have received sufficient explanation regarding participation in this study, have fully understood it, and have provided written consent of their own free will
Exclusion criteria
Exclusion criteria: Patients for whom pain evaluation is difficult (e.g., due to dementia, agitation, mental illness, etc.) Patients undergoing reoperation on the same side Patients scheduled for bilateral surgery Patients with renal dysfunction (as indicated by creatinine (Cre): male>1.07, female>0.79) Patients with liver dysfunction (AST or ALT = or more 100) Patients with an allergy to local anesthetics Cases deemed unsuitable by the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the Numerical Rating Scale (NRS) during movement 4 hours after returning to the room. The NRS ranges from 0 (no pain) to 10 (worst imaginable pain). | — |
Secondary
| Measure | Time frame |
|---|---|
| the presence or absence of additional analgesics from the time of returning to the room until the primary outcome measurement Intraoperative evaluation items: Intraoperative narcotic (remifentanil) usage, time from the end of surgery to extubation, presence of shivering, nausea, and use of antiemetics after extubation, highest blood pressure, maximum blood pressure change, maximum heart rate Acute pain assessment during hospitalization: NRS at rest and during movement on POD0 (upon return to the room, 12 hours (just before the second Acetaminophen administration)), and on POD1-4 (during vital signs measurement) Usage of analgesics Quality of life (QOL) assessment: QOL assessment using the EQ5D and the SF-36 scale before surgery and at 3 months postoperatively, and evaluation of chronic pain (NRS at 3 months follow-up or by mail) | — |
Contacts
Public ContactYasuharu Sekine
University of Tsukuba Hospital
Outcome results
None listed