Diseases that require general anesthesia in the operating room
Conditions
Interventions
Assign anesthesia maintenance to propofol group and remimazolam group.
In the propofol group, propofol 2-2.5 mg/kg was administered intravenously, and in the remimazolam group, remimazolam 12 mg/kg/ho
Sponsors
Sato Hanae
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Persons who are between 18 and 65 years old at the time of obtaining consent (pre-operative examination) 2) Cases with American Society of Anesthesiologists pre-anesthesia risk assessment 2 or lower (ASA classification 1: No organic, physiological, biochemical or mental abnormality. 2: Mild to moderate systematic disorder. 3: Severe systematic disorder. 4: Severe systematic disease that is threatening life and cannot be cured even with surgery.) 3) Subjects who have received sufficient explanation at the pre-operative examination to participate in this study, and who have given their voluntary written informed consent with full understanding.
Exclusion criteria
Exclusion criteria: 1)Patients with autonomic nerve imbalance 2)Patients with hypertension 3) Cases with moderate to severe systemic complications (American Society of Anesthesiologists preanesthesia risk assessment 3 or higher) 4)Poorly controlled diabetic patients 5) Patients taking oral medications that affect the autonomic nervous system 6)Other persons who are judged by the research director to be inappropriate as research subjects. 7) Persons who have requested refusal to participate in this research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spontaneous fluctuation waveforms of heart rate and blood pressure obtained from electrocardiogram and arterial pressure waveforms | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate, blood pressure, cardiac output, respiratory rate, end-tidal carbon dioxide concentration, percutaneous arterial oxygen saturation, BIS value | — |
Contacts
Public ContactHanae Sato
Nihon University School of Medicine
Outcome results
None listed